Pfizer Senior Scientist, Formulation Development in St. Louis, Missouri
Wh y Patients Need You
Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.
What You Will Achieve
As a Senior Scientist, you will be at the center of our operations and you'll find that everything we do, every day, is in line with an unwavering commitment to quality. You will be part of the Pharmaceutical Research and Development team that is focusing on utilizing genes as medicines to treat rare genetic diseases. The candidate will lead formulation development, scale-up, and transfer of gene therapy adeno associated virus (AAV) modalities. This is a project-based position performing formulation and process development activities for gene therapies from pre-clinical and Ph I clinical trials through manufacturing process performance qualification, license application and commercialization. You will be recognized as a technical expert and a scientific contributor. With your deep knowledge of the discipline, your decisions will impact the success of projects. You will be a critical member of our team developing formulations that ensure the stability of AAV-based therapeutics. You will be using your scientific judgment to adapt standard methods and techniques by applying prior work experience. You will be forecasting and planning resource requirements for your project team. Your creativity in developing novel processes and new ideas will be used frequently. You will undertake mentoring activities to guide team members. It is your innovative scientific temperament that will help in making Pfizer ready to achieve new milestones and help patients across the globe.
How You Will Achieve It
Contribute and influence at the project team level.
Interface with, provide formulation knowledge and expertise, and communicate the interpretation and implication of results to drug discovery teams and Pharmaceutical Science project teams.
Conduct solid state physical and chemical characterization of small molecules of pharmaceutical relevance, including particle characterization and solid state characterization.
Lead and plan formulation/process development assignments and activities to meet established project goals and timelines.
Maintain an awareness of and contribute to current scientific literature.
B.S. in Pharmaceutics, Chemistry, Chemical/Biochemical.
Engineering,Pharmacy,Biochemistry,Bioengineering,Biotechnology,Biology, Biomedical engineeringand at least 9 years industry or equivalent experience.
M.S. in Pharmaceutics, Chemistry, Chemical/ Biochemical, Engineering, Pharmacy,Biochemistry,Bioengineering,Biotechnology,Biology, Biomedical engineeringand at least 7 years industry or equivalent experience.
PhD. in Pharmaceutics, Chemistry, Chemical/Biochemical Engineering,Pharmacy, Biochemistry,Bioengineering,Biotechnology,Biology, Biomedical engineering.
B.S. with 9 or more years of industry experience in parenteral formulation andprocess development ofbiotherapeutics.
M.S. with 7 or more years of industry experience in parenteral formulation andprocess development ofbiotherapeutics.
PhD. with 1 to 3 years of industry experience in gene therapy formulation andprocess development ofbiotherapeutics.
Excellent leadership skills.
Expert understanding and leadership of technical area necessary for biotherapeutic molecule formulation development.
Experience in scale-up and technology transfer of aseptic processes to pilot/commercial scale manufacturing facilities.
Solid understanding of thermodynamics and kinetics.
Working knowledge of GLP/GMP requirements.
Experience in authoring regulatory submissions (IND, IMPD, BLA, MAA).
Solid understanding of QbD concept in design, execution, and interpretation of formulation and process development experiments.
Ability to demonstrate autonomy in representing functional area.
Communicates well in written form and verbally across functional areas and large groups.
Other Job Details:
Eligible for Relocation Package: YES
Eligible for Employee Referral Bonus: YES
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EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.
Research and Development