Thermo Fisher Scientific Scientist III, Cell Culture Development in St. Louis, Missouri

Job Description

When you’re part of the team at Thermo Fisher Scientific, you’ll do important work, like helping customers in finding cures for cancer, protecting the environment or making sure our food is safe. Your work will have real-world impact, and you’ll be supported in achieving your career goals.

Location/Division Specific Information

St. Louis, MO | Relocation is available

How will you make an impact?

This is an advanced level scientist position in the Cell Culture Development group.

What will you do?

  • Design and develop mammalian cell culture processes to support the production and manufacturing of recombinant proteins (including mAbs) under varying levels of direction, including but not limited to, cell culture scaleup, media development, harvest (recovery) process development, process range finding, and statistical analysis of data.

  • Perform media optimization, bioreactor process development, and cell culture clarification.

  • Design experimental plans based on defined deliverables, planning the activities to meet the project timelines by working closely with project managers.

  • Conduct moderately complex analyses to support process development. Work with Process Development and Manufacturing groups to trouble-shoot process challenges.

  • Record results in notebook accurately, clearly and regularly.

  • Prepare protocols, reports and test methods as well as write SOPs.

  • Execute appropriately, record, and evaluate experimental data, including the writing and revising of process development reports and technology transfer protocols as needed.

  • Remain current in the field by review of relevant scientific literature and attendance at appropriate scientific seminars and conferences.

  • Maintain and ensure safe laboratory environment and work practices.

How will you get here?

Education

  • Bachelor's degree or Master’s degree in biology, chemistry, biochemistry, chemical engineering, or a related field.

Experience

  • With Bachelor’s degree, minimum of 5 years of experience related to pharmaceutical manufacturing, process development. Experience using design of experiments (DoE) software (i.e. MiniTab, JMP) preferred.

  • With Master’s degree, 3 years of experience related to pharmaceutical manufacturing, process development. Experience using advanced statistical software packages and experience using design of experiments (DoE) software (i.e. MiniTab, JMP) preferred.

  • Prior experience with bioreactors required.

  • Prior Upstream Process Development experience required.

  • Must have mammalian cell culture experience in industry.

Knowledge, Skills, Abilities

  • Working knowledge of GMP/ GLP regulations in cGMP/ cGLP manufacturing environment.

  • Excellent problem solving and critical thinking skills.

  • Solid writing, communication and presentation skills.

  • Strong MS Excel, PowerPoint and Word skills.

  • Excellent organization and planning skills.

  • Strong attention to detail and ability to adhere to standards procedures.

  • Ability to design and execute tasks and studies based on the deliverables.

  • Ability to analyze and summarize complex scientific data.

  • Ability to create reports.

  • Ability to function in a rapidly changing environment.

  • Strong attention to detail and ability to adhere to standards procedures.

  • Ability to read, analyze, and interpret general business periodicals, professional journals, technical procedures, or governmental regulations.

  • Ability to speak effectively before groups of customers and employees.

  • Ability to make decisions that require choosing between limited alternatives to resolve complex problems.

  • Ability to perform all required process steps.

  • Ability to apply complex mathematical concepts to physical problems in areas.

  • Ability to lead and mentor less experienced staff.

At Thermo Fisher Scientific, each one of our 65,000 extraordinary minds has a unique story to tell. Join us and contribute to our singular mission—enabling our customers to make the world healthier, cleaner and safer.

Apply today! http://jobs.thermofisher.com

Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.

If you are an individual with a disability who requires reasonable accommodation to complete any part of our application process, click here at https://jobs.thermofisher.com/page/show/eeo-affirmative-action-statement#accessibility for further assistance.

Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.