Washington University of St. Louis Renal in St. Louis, Missouri

Post Doc Instructions

Please do not submit an application to this posting. To apply for this postdoctoral research opportunity, follow the directions below in “Applicant Special Instructions”.

Job Type/Schedule

This position is full-time and works approximately 40 hours per week.

Department Name/Job Location

This position is in the Department of Internal Medicine, Renal Division. This position is for the Medical School Campus.

Essential Functions

POSITION SUMMARY:

A Postdoctoral Research Associate position is available immediately to study molecular and genetic mechanisms of normal development and diseases of the genitourinary and bladder nervous system in the Jain Lab at Washington University School of Medicine in St. Louis. We are investigating the basis for heterogeneity in progenitor populations during different stages of development, injury and regeneration using single cell or bulk population sequencing. One objective is to build gene regulatory networks that will help generate the blueprint for formation of key structures of the kidney. We wish to determine how this information can be used to design or engineer kidney substructures from pluripotent stem cells in vitro (iPSCs) and for therapy, toxicity screening and mechanistic understanding of patients with congenital kidney defects. Experience in analysis of gene expression datasets using bulk or single cell next generation sequencing technologies and wet lab work is preferred. Already existing resources include exome sequencing data of more than 150 patients with renal malformations, battery of kidney and urinary tract reporter mice, GDNF-RET signaling mutant mice, and pooled and single cell NGS data of developmental series of ENS, sensory neurons and collecting system progenitors expressing RET receptor tyrosine kinase. Candidates may access jainlab.im.wustl.edufor further information regarding research in the laboratory.

The Washington University Renal Division (https://renal.wustl.edu/) has been ranked as top ten by US News & World Report every year since ratings began. The research environment is outstanding.

Required Qualifications

The appointee has earned a Ph.D., M.D. or equivalent terminal or doctoral degree.

Preferred Qualifications

  • A PhD or MD/PhD degree in molecular biology, biochemistry, genetics, cell biology or other related fields.
  • Experience with mouse models, fine skills in dissection, stem cell culture and analysis of gene expression data sets using next generation sequencing technologies are preferred.

Salary Range

Base pay commensurate with experience.

Benefits

This position is eligible for full-time benefits. Please visit our website at http://hr.wustl.edu to view a summary of benefits.

Applicant Special Instructions

Candidates with expertise (first author publication in peer reviewed journal) and interest are requested to apply early. Submit CV, and names of 3 references to:

Sanjay Jain, MD, PhD

Associate Professor: Medicine (Nephrology), Pathology and Immunology

Director, Kidney Translational Research Core (KTRC)

Washington University School of Medicine, Box 8126

Wohl Clinic Rm 8843

660 S. Euclid Ave, St. Louis, MO 63110

Office:314-454-8728; Lab:314-454-8464; Fax:314-454-7735.

email: sanjayjain@wustl.edu

jainlab.im.wustl.edu

EOE Statement

Washington University is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, genetic information, disability, or protected veteran status.

Job Title: Postdoctoral Research Associate - Renal - 41548

Job ID: 41548

Location: Medical School

Full/Part Time: Full-Time

Regular/Temporary: Regular