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Washington University of St. Louis Postdoctoral Research Associate - Bone Marrow Transplant - 51753 in St. Louis, Missouri

Post Doc Instructions Please do not submit an application to this posting. To apply for this postdoctoral research opportunity, follow the directions below in “Applicant Special Instructions”. Department Name/Job Location This position is in the Department of Internal Medicine, Division of Oncology. This position is for the Medical School Campus. Essential Functions POSITION SUMMARY: Area of expertise: Immunology and Genomics The Singh Lab at the Washington University School of Medicine, Division of Oncology is seeking a postdoctoral fellow to study techniques to improve cellular immunotherapy for blood cancers. Our laboratory is broadly interested in the mechanisms by which chimeric antigen receptors (CARs) regulate effective and dysfunctional T cell responses against cancer. Using classical immunologic techniques, novel genomic interrogations and advanced genome and protein engineering, we aim to use a detailed understanding of the molecular circuitry driven by CARs and other synthetic antigen receptors to design improved immunotherapies. This specific project will likely involve CRISPR-based genome editing, single-cell RNA and ATAC sequencing, and functional assessments of engineered human T cells. Successful candidates should have a strong publication record and background in immunology or genomics. In addition to high-quality research facilities, career and professional development training for postdoctoral researchers is provided through the Career Center, Teaching Center, Office of Postdoctoral Affairs, and campus groups. Additional information on being a postdoc at Washington University in St. Louis can be found at postdoc.wustl.edu/prospective-postdocs. PRIMARY DUTIES AND RESPONSIBILITIES: Trains under the supervision of a faculty mentor, including (but not limited to): 1. Manages their own project, which should lead to several first author publications. 2. Develops expertise in human T cell engineering, translational immunology and development of clinical cellular immunotherapy products, synthetic protein design, analysis of genomics datasets. 3. Develops proficiency in career skills, including writing, public speaking, networking, and critical evaluation of scientific literature. 4. Presents scientific work both inside and outside the University with excellent oral communication skills. 5. Assists with grant preparation and reporting. 6. Prepares and submits papers on research with excellent writing skills. 7. Designs research experiments. 8. Evaluates research findings and reports results. 9. Maintains conscientious discharge of their research responsibilities. 10. Maintains conformity with ethical standards in research. 11. Maintains compliance with good laboratory practice, including the maintenance of adequate research records. 12. Engages in open and timely discussion with their mentor regarding possession or distribution of material, reagents, or records belonging to their laboratory and any proposed disclosure of findings or techniques privately or in publications. 13. Maintains collegial conduct towards co-trainees, staff members and members of the research group. 14. Adheres to all applicable University policies, procedures and regulations. All data, research records and materials and other intellectual property generated in University laboratories remain the property of the University. Required Qualifications Ph.D., M.D. or an equivalent terminal or doctoral degree. Preferred Qualifications * Experience in laboratory immunology, preferably working with human T cells. * Experience in genetic engineering, single-cell genomics or bioinformatics would significantly strengthen the application. * Excellence in laboratory techniques, including flow cytometry, sterile cell culture, western blotting, preparation of samples for next-generation sequencing, basic sequencing analysis and CRISPR genome editing. * Outstanding communication and collaborative work skills. Salary Range Base pay commensurate with experience. Pre-Employment Screening All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. Current employees applying for a new position within the university may be subject to this requirement. The screenings will include a criminal background check and, as applicable for the position, other background checks, drug screen, employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening. Benefits This position is eligible for full-time benefits. Please click the following link to view a summary of benefits: https://hr.wustl.edu/benefits/. Applicant Special Instructions Interested candidates should submit their curriculum vitae, statement of research interests and contact information of three references via email to Dr. Nathan Singh at nathan.singh@wustl.edu. EOE Statement Washington University is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, genetic information, disability, or protected veteran status. Job Title: Postdoctoral Research Associate - Bone Marrow Transplant - 51753 Job ID: 51753 Location: Medical School Full/Part Time: Full-Time Regular/Temporary: Regular

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