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Bayer Sr. Scientist Computational Chemist in Creve Coeur, Missouri

Bayer is a global enterprise with core competencies in the Life Science fields of health care and agriculture. Its products and services are designed to benefit people and improve their quality of life. At Bayer you have the opportunity to be part of a culture where we value the passion of our employees to innovate and give them the power to change.

Sr. Scientist Computational Chemist


The primary responsibilities of this role, Senior Scientist Computational Chemist, are to:

  • Structure and ligand-based compound design including virtual screening Cheminformatics techniques for molecular target selection, HTS analysis, and data visualization;

  • Work on structural bioinformatics, homology modeling, target class similarity assessment, target and lead based design of compounds;

  • Apply agile in silico modeling technologies for small synthetic molecules as well as biomolecules i.e. peptides, oligonucleotides or natural compounds;

  • Work on prediction of compound physicochemical properties to aid in compound design and selection;

  • Evaluate novel internal and external computational capabilities;

  • Generate and secure IP for all projects;

  • Contribute to data science initiatives and interface development within crop protection discovery and crop protection discovery.


Your success will be driven by your demonstration of our LIFE values. More specifically related to this position, Bayer seeks an incumbent who possesses the following:

Required Qualifications:

  • Bachelor’s degree with at least 10 years of relevant experience, or Master’s degree at least eight years of relevant experience or Ph.D. with at least four years of experience;

  • Four years of computational chemistry experience within a pharmaceutical, agrochemical or biotechnology setting;

  • Demonstrated impact in applying computational chemistry to drive the design and progression of small molecules in a team setting as evidenced by publications and patent applications;

  • Demonstrated experience in applying computing workflows with biomolecules as peptides, sRNA, natural products or high molecular weight molecules;

  • Experience in team-based small molecule design in early to late stage discovery;

  • Ability to work in a cross disciplinary team environment with strong interpersonal and communication skills.

Preferred Qualifications:

  • Degree in Chemistry, Biochemistry, Structural Biology, Computational Chemistry or related field with at least four years of relevant experience;

  • Knowledge of novel modalities and approaches to identifying and modeling interactions that govern these modalities;

  • Experience in plant systems.



Bayer offers a wide variety of competitive compensation and benefits programs. If you meet the requirements of this unique opportunity, and you have the "Passion to Innovate" and the "Power to Change", we encourage you to apply now. To all recruitment agencies: Bayer does not accept unsolicited third party resumes.

Bayer is an Equal Opportunity Employer/Disabled/Veterans

Bayer is committed to providing access and reasonable accommodations in its application process for individuals with disabilities and encourages applicants with disabilities to request any needed accommodation(s) using the contact information below.

Location: United States : Missouri : Brookfield || United States : Missouri : Chesterfield || United States : Missouri : Creve Coeur || United States : Missouri : Hazelwood || United States : Missouri : Joplin || United States : Missouri : Kansas City || United States : Missouri : Liberty || United States : Missouri : Marshall || United States : Missouri : Matthews || United States : Missouri : New Haven || United States : Missouri : Owensville || United States : Missouri : Residence Based || United States : Missouri : Saint Joseph || United States : Missouri : Sikeston || United States : Missouri : St. Louis

Division: Crop Science

Reference Code: 340602

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